Uganda’s latest Ebola outbreak, which I covered back in July, was just officially declared over on October 5th, a mere two weeks ago. Now today there is a report that three are dead from an outbreak of Marburg virus. That makes 4 Ebola outbreaks and now 2 Marburg outbreaks in the country since 2000.
As I’ve noted before, filoviruses are some of my favorite pathogens. I don’t work on them myself–though in the pre-children era I certainly thought about it–but I find them absolutely fascinating to read about and follow the literature. Mostly, I think, this is because after knowing about them for so many years (Marburg was discovered in 1967), and so much research (over 1500 papers in Pubmed, or roughly a paper for every person these viruses have killed), we still know relatively little about the most basic questions–such as where there viruses are maintained in nature, and how they enter the human (or non-human primate) population, and why they’re so deadly.
Anyway, after a long time in Ebola’s shadow, Marburg virus has been in the news recently. As such, this is part one in a mini-series on Marburg virus, with an introduction to the virus and its history after the jump.